Quick Answer: What Happens If RDW Is High?

Is high RDW a sign of cancer?

RDW is elevated when there is increased red cell destruction, or, more commonly, ineffective red cell production.

RDW may represent nutritional deficiency (e.g., iron, vitamin B12, or folic acid), bone marrow depression, or chronic inflammation [30–32].

These conditions are more or less prevalent in cancers..

How do you reduce Rdw?

When MCV is low, RDW would increase more significantly. When iron therapy is given, RDW would elevate first and then gradually reduce at the normal level. To diagnose small cell and low pigment anaemia. To classify anaemia.

Is a high RDW dangerous?

Red cell distribution width (RDW) has recently been associated with the risk of cardiovascular disease and all-cause mortality. The underlying mechanisms remain unresolved, but high levels of RDW may be caused by inflammation or poor nutritional status.

What does it mean when RDW is high and MCV is normal?

Normal RDW and high MCV. This can indicate a liver condition or alcohol abuse. Or, a person may have this result because they are on antiviral drugs or chemotherapy. If other blood characteristics are also affected, this can suggest aplastic anemia, a rare disorder caused by inadequate blood cell production.

Does high MCV mean cancer?

Conclusions: This study suggests that the elevated MCV level in non-anemic cancer-free individuals was associated with increased all-cause mortality in both men and women, and with cancer mortality, in particular liver cancer mortality in men. Future prospective studies are required to consolidate our findings.

What level of RDW is dangerous?

A high RDW (over 14.5%) means that the red blood cells vary a lot in size. A normal RDW is 11.6 to 14.6%, but researchers from the Intermountain Medical Center Heart Institute found that patients with a RDW level greater than or equal to 12.9% had an increased risk for depression.

Why is Rdw high in iron deficiency anemia?

However, a varied size distribution of red blood cells is a hallmark of iron deficiency anemia, and as such shows an increased RDW in virtually all cases. In the case of both iron and B12 deficiencies, there will normally be a mix of both large cells and small cells, causing the RDW to be elevated.

What blood test can indicate cancer?

Complete blood count (CBC). This common blood test measures the amount of various types of blood cells in a sample of your blood. Blood cancers may be detected using this test if too many or too few of a type of blood cell or abnormal cells are found. A bone marrow biopsy may help confirm a diagnosis of a blood cancer.

What does Rdw mean in a blood count?

A red cell distribution width (RDW) test is a measurement of the range in the volume and size of your red blood cells (erythrocytes). Red blood cells move oxygen from your lungs to every cell in your body. Your cells need oxygen to grow, reproduce, and stay healthy.

What is Microcytic anemia?

Microcytic anemia is defined as the presence of small, often hypochromic, red blood cells in a peripheral blood smear and is usually characterized by a low MCV (less than 83 micron 3). Iron deficiency is the most common cause of microcytic anemia.

What does a low RDW mean?

A low RDW (below 10.2%) means that the red blood cells vary very little in size. One reason for a low RDW level is macrocytic anemia. Another cause of a low RDW level is microcytic anemia.

What is the normal range for Rdw SD?

The width of the distribution curve is measured at the point that is 20% above the baseline. Since the RDW-SD is an actual measurement, it is not influenced by the MCV and more accurately reflects the red cell size variance. The normal RDW-SD range for adults is 40.0 – 55.0 fL.

Does RDW 16.4 mean?

A high RDW means you have both very small and very large red blood cells. You may also have a “normal” RDW. A normal RDW range is 12.2%–16.1% for women and 11.8%–14.5% for men.

Is high RDW serious?

If your RDW is too high, it could be an indication of a nutrient deficiency, such as a deficiency of iron, folate, or vitamin B-12. These results could also indicate macrocytic anemia, when your body doesn’t produce enough normal red blood cells, and the cells it does produce are larger than normal.

What are the symptoms of high red blood cell count?

If you have a high RBC count, you could experience symptoms such as:fatigue.shortness of breath.joint pain.tenderness in the palms of the hands or soles of the feet.itching skin, particularly after a shower or bath.sleep disturbance.